Researchers at the University of Michigan School of Public Health have found liver tumors in mice exposed to the plastics chemical BPA via their mothers during gestation and nursing. It's one of the first studies to show a significant link between BPA and cancer development.
"We found that 27 percent of the mice exposed to one of three different doses of BPA through their mother's diet developed liver tumors and some precancerous lesions. The higher the dosage, the more likely they were to present with tumors," said Caren Weinhouse, U-M doctoral student in the School of Public Health's Department of Environmental Health Sciences and first author of the paper published online Feb. 3 in Environmental Health Perspectives.
Editor’s Note: New 'Obamacare Survival Guide' Reveals Dangers Ahead for Your Healthcare
http://www.writerscafe.org/writing/jasminejesper370/1312943/
Mice whose mothers received the highest dosage, 50 mg of BPA in every kilogram of food (about two pounds), were seven times more likely to have tumors than those whose mothers were not exposed to BPA.
The researchers said more research is needed to determine the implications for human health.
"This current study showing liver tumors in mice says let's take another look at BPA and cancer in humans," Weinhouse said, adding that next the lab will look for biomarkers in the mice genes that may signal risk for disease before it develops, and then try to see if similar characteristics are found in humans.
Bisphenol A, or BPA, is a chemical most commonly found in plastics, cash register receipts and the lining of food cans. It once was used in hard plastic bottles, including baby bottles, but many companies have removed it as concerns about health effects have been raised in recent years. Studies have estimated that at least 90 percent of Americans have some level of BPA in their bodies.
Previous research has found precancerous lesions associated with BPA exposure but the U-M study is the first statistically significant finding of clinically evident tumors in any organ, said Dana Dolinoy, the John G. Searle Assistant Professor of Environmental Health Sciences and senior/corresponding author of the study. Specifically, the researchers found that adult offspring of exposed mothers had an increase in liver tumors.
Dolinoy said another interesting finding in their research is that tumor development didn't discriminate by sex.
"In general, females are at lower risk of spontaneous development of liver cancer," she said. "That distinction was erased in this study, with both males and females showing tumors."
The researchers fed 6-week-old female mice diets containing one of three environmentally relevant doses of BPA prior to mating, then throughout pregnancy and nursing. They then took one male and one female from each litter and followed them through to 10 months.
Another point of interest in their research, Dolinoy said, is that most other small animal studies have involved direct exposure to BPA. In this research, it was the mothers who were exposed before conception. The offspring, therefore, were exposed as developing fetuses and pups, not as adults.
"A previous study that exposed adult mice to much higher doses of BPA did not show the same link to cancer development," she said. "This tells us the timing of exposure and the dosage are extremely critical in evaluating study outcomes."
One year ago, Dolinoy's lab found BPA in human fetal liver tissue, demonstrating that there is considerable exposure to the chemical during pregnancy. In that study, they also found a proportionately higher concentration of free BPA—as opposed to conjugated forms modified by the body for elimination—showing that the ability to flush the chemical from the body is not the same in fetuses as in adults.
Monday, February 10, 2014
'Third-Hand' Smoke is Deadly: Expert
Third-hand smoke" — the invisible remnant of tobacco smoke that clings to surfaces and even dust — has been linked to several adverse health effects in a new study published in the Public Library of Science journal PLOS ONE.
While the secondhand smoke can be seen wafting through the air, researchers from the University of California-Riverside noted third-hand smoke is a more hidden health threat, but concluded it can be just as deadly.
Editor's Note: Knowing these 5 cancer-causing signs is crucial to remaining cancer-free for life
That conclusion is based on new first-ever studies of the effects of third-hand smoke on laboratory mice, which the researchers said have important implications for people. http://healthcares.snack.ws/reduce-the-chances-of-developing-various-diseases-amanda-leto-review.html
"We studied, on mice, the effects of third-hand smoke on several organ systems under conditions that simulated third-hand smoke exposure of humans," said Manuela Martins-Green, a professor of cell biology who led the study. "We found significant damage occurs in the liver and lung. Wounds in these mice took longer to heal. Further, these mice displayed hyperactivity."
Third-hand smoke, which contains strong carcinogens, is a potential health threat to children, spouses of smokers, and workers in environments where smoking is allowed, the researchers said. Contamination of the homes of smokers by third-hand smoke is high, both on surfaces and in dust, including children's bedrooms.
The UC team found that the mice exposed to third-hand smoke in the lab showed alterations in multiple organ systems and excreted levels of a tobacco-specific carcinogen similar to those found in children exposed to second-hand smoke.
In the liver, third-hand smoke was found to increase cholesterol levels and non-alcoholic fatty liver disease, a precursor to cirrhosis and cancer and a potential contributor to cardiovascular disease. In the lungs, third-hand smoke was found to increase risks tied to inflammation-induced diseases such as chronic obstructive pulmonary disease and asthma. Mice exposed to third-hand smoke also showed signs of hyperactivity.
"There is a critical need for animal experiments to evaluate biological effects of exposure to third-hand smoke that will inform subsequent human epidemiological and clinical trials," Martins-Green said. "Such studies can determine potential human health risks, design of clinical trials and potentially can contribute to policies that lead to reduction in both exposure and disease."
Editor's Note: Knowing these 5 cancer-causing signs is crucial to remaining cancer-free for life
While the secondhand smoke can be seen wafting through the air, researchers from the University of California-Riverside noted third-hand smoke is a more hidden health threat, but concluded it can be just as deadly.
Editor's Note: Knowing these 5 cancer-causing signs is crucial to remaining cancer-free for life
That conclusion is based on new first-ever studies of the effects of third-hand smoke on laboratory mice, which the researchers said have important implications for people. http://healthcares.snack.ws/reduce-the-chances-of-developing-various-diseases-amanda-leto-review.html
"We studied, on mice, the effects of third-hand smoke on several organ systems under conditions that simulated third-hand smoke exposure of humans," said Manuela Martins-Green, a professor of cell biology who led the study. "We found significant damage occurs in the liver and lung. Wounds in these mice took longer to heal. Further, these mice displayed hyperactivity."
Third-hand smoke, which contains strong carcinogens, is a potential health threat to children, spouses of smokers, and workers in environments where smoking is allowed, the researchers said. Contamination of the homes of smokers by third-hand smoke is high, both on surfaces and in dust, including children's bedrooms.
The UC team found that the mice exposed to third-hand smoke in the lab showed alterations in multiple organ systems and excreted levels of a tobacco-specific carcinogen similar to those found in children exposed to second-hand smoke.
In the liver, third-hand smoke was found to increase cholesterol levels and non-alcoholic fatty liver disease, a precursor to cirrhosis and cancer and a potential contributor to cardiovascular disease. In the lungs, third-hand smoke was found to increase risks tied to inflammation-induced diseases such as chronic obstructive pulmonary disease and asthma. Mice exposed to third-hand smoke also showed signs of hyperactivity.
"There is a critical need for animal experiments to evaluate biological effects of exposure to third-hand smoke that will inform subsequent human epidemiological and clinical trials," Martins-Green said. "Such studies can determine potential human health risks, design of clinical trials and potentially can contribute to policies that lead to reduction in both exposure and disease."
Editor's Note: Knowing these 5 cancer-causing signs is crucial to remaining cancer-free for life
Colon Camera Pill Gets FDA OK
Camera-in-a-pill maker Given Imaging said on Monday it received U.S. Food and Drug Administration clearance for a pill to provide visualization of the colon that has a global market of 3 million procedures a year.
The pill, called the PillCam Colon, may be used for detection of colon polyps in patients after an incomplete optical colonoscopy, the Israeli medical device maker said.
There are 750,000 patients in the United States alone who experience an incomplete colonoscopy each year, Given Imaging said, and they often incur additional costs, along with the inconvenience and risk associated with other procedures to complete the colorectal examination. http://reviewlity.blogspot.com/2014/02/with-regard-to-health-and-cleanliness.html
Given Imaging is a developer of technology for visualizing, diagnosing and monitoring the digestive system, including its PillCam, a swallowed capsule endoscope.
In December, medical device maker Covidien PLC said it would acquire Given Imaging for $860 million. The transaction is expected to be completed by March 31.
The pill, called the PillCam Colon, may be used for detection of colon polyps in patients after an incomplete optical colonoscopy, the Israeli medical device maker said.
There are 750,000 patients in the United States alone who experience an incomplete colonoscopy each year, Given Imaging said, and they often incur additional costs, along with the inconvenience and risk associated with other procedures to complete the colorectal examination. http://reviewlity.blogspot.com/2014/02/with-regard-to-health-and-cleanliness.html
Given Imaging is a developer of technology for visualizing, diagnosing and monitoring the digestive system, including its PillCam, a swallowed capsule endoscope.
In December, medical device maker Covidien PLC said it would acquire Given Imaging for $860 million. The transaction is expected to be completed by March 31.
At-Home Test Spots Most Colon Cancers: Review
An at-home test that reacts to blood in a person's stool can identify most colon cancers, according to a fresh look at some previous studies.
Researchers found the fecal immunochemical test (FIT) is able to detect 79 percent of colorectal cancers without making people change their diets or stop taking their medications, as some other screening tests require.
"It's more user friendly for the patient," Dr. Jeffrey Lee told Reuters Health.
Lee, from the University of California, San Francisco and Kaiser Permanente Northern California Division of Research, led the analysis. http://www.writerscafe.org/writing/jasminejesper370/1312943/
Colon cancer is the second leading cause of cancer-related deaths in the U.S., according to the Centers for Disease Control and Prevention (CDC). About 132,000 people were diagnosed with the disease in 2010 and about 52,000 died from it.
The government-backed U.S. Preventive Services Task Force (USPSTF) recommends people between ages 50 and 75 get screened by colonoscopy every 10 years.
During a colonoscopy, a doctor uses a long flexible tube equipped with a tiny video camera to see the interior of the colon.
Alternatively, the USPSTF says people in that age group can have a high-sensitivity fecal occult blood test every year, or a sigmoidoscopy - which is similar to a colonoscopy - every five years in addition to fecal occult blood testing every three years.
Fecal occult blood testing (FOBT) is more cumbersome than FIT, Lee said. It requires more samples and more pre-test changes to a person's diet and medication schedule.
According to the USPSTF's website, the panel is currently planning to analyze the effectiveness of FIT.
For the new study, published in the Annals of Internal Medicine, the researchers searched databases of medical research for studies from 1996 through 2013 that looked at the effectiveness of FIT.
They included 19 studies in their final analysis. The studies each included between about 100 and 28,000 people with no symptoms of colon cancer.
In most cases, the participants used FIT and then were screened with a colonoscopy soon afterward.
The researchers found FIT detected 79 percent of colon cancers after one test. Among people who didn't have colon cancer, 94 percent tested negative.
For comparison, FOBT has a reported accuracy between 13 and 50 percent, according to the researchers.
While FOBT costs about $5 per test, the average cost of FIT is about $22, according to the patient advocacy organization Colon Cancer Alliance, Inc.
"Our study kind of confirms that FIT is an accurate test, but ultimately my take-home message is that there are so many options for screening," Lee said.
Janet Byron, a spokesperson for the Kaiser Permanente Division of Research, told Reuters Health in an email that Kaiser Permanente Northern California implemented systemwide FIT testing for adults between 50 and 75 years old. The kits are distributed by mail, at doctors' offices and in labs.
The healthcare system has a cancer screening rate of about 80 percent. That compares to the approximately 70 percent of people in that age range who are screened nationally, according to the CDC.
Assuming people use it, FIT could lead to a greater reduction in colon cancer deaths above what FOBT has already done, according to Lee.
"I just recommend that for the general population to get screened," he said. "The best test is the one that actually gets done."
Researchers found the fecal immunochemical test (FIT) is able to detect 79 percent of colorectal cancers without making people change their diets or stop taking their medications, as some other screening tests require.
"It's more user friendly for the patient," Dr. Jeffrey Lee told Reuters Health.
Lee, from the University of California, San Francisco and Kaiser Permanente Northern California Division of Research, led the analysis. http://www.writerscafe.org/writing/jasminejesper370/1312943/
Colon cancer is the second leading cause of cancer-related deaths in the U.S., according to the Centers for Disease Control and Prevention (CDC). About 132,000 people were diagnosed with the disease in 2010 and about 52,000 died from it.
The government-backed U.S. Preventive Services Task Force (USPSTF) recommends people between ages 50 and 75 get screened by colonoscopy every 10 years.
During a colonoscopy, a doctor uses a long flexible tube equipped with a tiny video camera to see the interior of the colon.
Alternatively, the USPSTF says people in that age group can have a high-sensitivity fecal occult blood test every year, or a sigmoidoscopy - which is similar to a colonoscopy - every five years in addition to fecal occult blood testing every three years.
Fecal occult blood testing (FOBT) is more cumbersome than FIT, Lee said. It requires more samples and more pre-test changes to a person's diet and medication schedule.
According to the USPSTF's website, the panel is currently planning to analyze the effectiveness of FIT.
For the new study, published in the Annals of Internal Medicine, the researchers searched databases of medical research for studies from 1996 through 2013 that looked at the effectiveness of FIT.
They included 19 studies in their final analysis. The studies each included between about 100 and 28,000 people with no symptoms of colon cancer.
In most cases, the participants used FIT and then were screened with a colonoscopy soon afterward.
The researchers found FIT detected 79 percent of colon cancers after one test. Among people who didn't have colon cancer, 94 percent tested negative.
For comparison, FOBT has a reported accuracy between 13 and 50 percent, according to the researchers.
While FOBT costs about $5 per test, the average cost of FIT is about $22, according to the patient advocacy organization Colon Cancer Alliance, Inc.
"Our study kind of confirms that FIT is an accurate test, but ultimately my take-home message is that there are so many options for screening," Lee said.
Janet Byron, a spokesperson for the Kaiser Permanente Division of Research, told Reuters Health in an email that Kaiser Permanente Northern California implemented systemwide FIT testing for adults between 50 and 75 years old. The kits are distributed by mail, at doctors' offices and in labs.
The healthcare system has a cancer screening rate of about 80 percent. That compares to the approximately 70 percent of people in that age range who are screened nationally, according to the CDC.
Assuming people use it, FIT could lead to a greater reduction in colon cancer deaths above what FOBT has already done, according to Lee.
"I just recommend that for the general population to get screened," he said. "The best test is the one that actually gets done."
Vitamin C Helps Chemo Fight Cancer: Study
Large doses of intravenous vitamin C have the potential to boost chemotherapy's ability to kill cancer cells, according to new laboratory research involving human cells and mice.
Vitamin C delivered directly to human and mouse ovarian cancer cells helped kill off those cells while leaving normal cells unharmed, University of Kansas researchers report.
"In cell tissue and animal models of cancer, we saw when you add IV vitamin C it seems to augment the killing effect of chemotherapy drugs on cancer cells," said study co-author Dr. Jeanne Drisko, director of integrative medicine at the University of Kansas Medical Center.
Editor's Note: Knowing these 5 cancer-causing signs is crucial to remaining cancer-free for life
In follow-up human trials, a handful of cervical cancer patients given intravenous vitamin C along with their chemotherapy reported fewer toxic side effects from their cancer treatment, according to the study published in the Feb. 5 issue of Science Translational Medicine. http://generalhealthcare2014.wordpress.com/2014/02/10/basic-spices-to-lose-weight-in-winter/
"In those patients, we didn't see any ill effects and we noticed they had fewer effects from the chemotherapy," Drisko said. "It seemed to be protecting the healthy cells while killing the cancer cells."
Intravenous vitamin C has been considered an integrative medical therapy for cancer since the 1970s, Drisko noted.
But vitamin C's cancer-killing potential hasn't been taken seriously by mainstream medicine ever since clinical trials performed by the Mayo Clinic with oral vitamin C in the late 1970s and early 1980s found no anti-cancer effects, she explained.
Researchers have since argued that those trials were flawed because vitamin C taken orally is absorbed by the gut and excreted by the kidneys before its levels can build up in the bloodstream.
But it's been hard to attract funding for further research. There's no reason for pharmaceutical companies to fund vitamin C research, and federal officials have been uninterested in plowing research dollars into the effort since the Mayo research was published, Drisko said.
This latest investigation began with researchers exposing human ovarian cancer cells to vitamin C in the lab. They found that the cells suffered DNA damage and died off, while normal cells were left unharmed.
The researchers then tested vitamin C on mice with induced ovarian cancer. The vitamin appeared to help chemotherapy drugs either inhibit the growth of tumors or help shrink them.
Finally, the team conducted a pilot phase clinical trial involving 27 patients with stage III or stage IV ovarian cancer.
The patients who received intravenous vitamin C along with their chemotherapy reported less toxicity of the brain, bone marrow and major organs, the investigators found.
These patients also appeared to add nearly 8.75 months to the time before their disease relapsed and progressed, compared with people who only received chemotherapy. The researchers did note that the study was not designed to test the statistical significance of that finding.
Vitamin C in the bloodstream helps kill cancer cells because it chemically converts into hydrogen peroxide when it interacts with tumors, Drisko said.
"If you can get your blood levels of vitamin C very high, it gets driven into the space around the cancer cells," she explained. "In that space, it's converted into hydrogen peroxide. It's very similar to what our white blood cells do. They create hydrogen peroxide to fight infection."
Dr. Stephanie Bernik, chief of surgical oncology at Lenox Hill Hospital in New York City, said intravenous vitamin C therapy is not unheard of among cancer doctors.
"I've had patients come in and say they were doing vitamin C intravenous therapy," Bernik said. "I always tell them we don't know enough to know whether it is good or bad."
This new research raises interesting possibilities, but until larger clinical trials are conducted Bernik says her advice to patients will not change.
"You have to do a bigger study with patients and look at outcomes. You also have to make sure these treatments don't interfere with the treatments we're giving currently," she said.
"There may be some efficacy in what they're doing. It just needs to be proven. This is just the start of more studies looking at this in-depth."
Dr. Michael Seiden, chief medical officer for The US Oncology Network, agreed.
"It is important to emphasize that many vitamin therapies have shown interesting results when applied to cancer cells in test tubes yet, to date, these approaches typically are not effective and occasionally prove harmful in human studies," he said. "At this time, there is still no evidence that high-dose vitamin C should be part of the treatment for women with ovarian cancer."
While she agreed that larger trials need to be conducted, Drisko was not as hesitant.
"It's safe. It's inexpensive. There's a plausible mechanism we're investigating for why it works," she said. "We should be using this in patients, rather than dragging our feet and worrying about using it at all."
Vitamin C delivered directly to human and mouse ovarian cancer cells helped kill off those cells while leaving normal cells unharmed, University of Kansas researchers report.
"In cell tissue and animal models of cancer, we saw when you add IV vitamin C it seems to augment the killing effect of chemotherapy drugs on cancer cells," said study co-author Dr. Jeanne Drisko, director of integrative medicine at the University of Kansas Medical Center.
Editor's Note: Knowing these 5 cancer-causing signs is crucial to remaining cancer-free for life
In follow-up human trials, a handful of cervical cancer patients given intravenous vitamin C along with their chemotherapy reported fewer toxic side effects from their cancer treatment, according to the study published in the Feb. 5 issue of Science Translational Medicine. http://generalhealthcare2014.wordpress.com/2014/02/10/basic-spices-to-lose-weight-in-winter/
"In those patients, we didn't see any ill effects and we noticed they had fewer effects from the chemotherapy," Drisko said. "It seemed to be protecting the healthy cells while killing the cancer cells."
Intravenous vitamin C has been considered an integrative medical therapy for cancer since the 1970s, Drisko noted.
But vitamin C's cancer-killing potential hasn't been taken seriously by mainstream medicine ever since clinical trials performed by the Mayo Clinic with oral vitamin C in the late 1970s and early 1980s found no anti-cancer effects, she explained.
Researchers have since argued that those trials were flawed because vitamin C taken orally is absorbed by the gut and excreted by the kidneys before its levels can build up in the bloodstream.
But it's been hard to attract funding for further research. There's no reason for pharmaceutical companies to fund vitamin C research, and federal officials have been uninterested in plowing research dollars into the effort since the Mayo research was published, Drisko said.
This latest investigation began with researchers exposing human ovarian cancer cells to vitamin C in the lab. They found that the cells suffered DNA damage and died off, while normal cells were left unharmed.
The researchers then tested vitamin C on mice with induced ovarian cancer. The vitamin appeared to help chemotherapy drugs either inhibit the growth of tumors or help shrink them.
Finally, the team conducted a pilot phase clinical trial involving 27 patients with stage III or stage IV ovarian cancer.
The patients who received intravenous vitamin C along with their chemotherapy reported less toxicity of the brain, bone marrow and major organs, the investigators found.
These patients also appeared to add nearly 8.75 months to the time before their disease relapsed and progressed, compared with people who only received chemotherapy. The researchers did note that the study was not designed to test the statistical significance of that finding.
Vitamin C in the bloodstream helps kill cancer cells because it chemically converts into hydrogen peroxide when it interacts with tumors, Drisko said.
"If you can get your blood levels of vitamin C very high, it gets driven into the space around the cancer cells," she explained. "In that space, it's converted into hydrogen peroxide. It's very similar to what our white blood cells do. They create hydrogen peroxide to fight infection."
Dr. Stephanie Bernik, chief of surgical oncology at Lenox Hill Hospital in New York City, said intravenous vitamin C therapy is not unheard of among cancer doctors.
"I've had patients come in and say they were doing vitamin C intravenous therapy," Bernik said. "I always tell them we don't know enough to know whether it is good or bad."
This new research raises interesting possibilities, but until larger clinical trials are conducted Bernik says her advice to patients will not change.
"You have to do a bigger study with patients and look at outcomes. You also have to make sure these treatments don't interfere with the treatments we're giving currently," she said.
"There may be some efficacy in what they're doing. It just needs to be proven. This is just the start of more studies looking at this in-depth."
Dr. Michael Seiden, chief medical officer for The US Oncology Network, agreed.
"It is important to emphasize that many vitamin therapies have shown interesting results when applied to cancer cells in test tubes yet, to date, these approaches typically are not effective and occasionally prove harmful in human studies," he said. "At this time, there is still no evidence that high-dose vitamin C should be part of the treatment for women with ovarian cancer."
While she agreed that larger trials need to be conducted, Drisko was not as hesitant.
"It's safe. It's inexpensive. There's a plausible mechanism we're investigating for why it works," she said. "We should be using this in patients, rather than dragging our feet and worrying about using it at all."
Daily Aspirin Protects Women Against Ovarian Cancer: Study
Taking aspirin every day might lower a woman's risk of developing ovarian cancer by one-fifth, a new study suggests.
Researchers from the U.S. National Cancer Institute analyzed data from 12 studies that involved nearly 8,000 women with ovarian cancer and close to 12,000 women without the disease to determine how the use of aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen (Tylenol) affected the risk of ovarian cancer.
About 18 percent of the women used aspirin regularly, 24 percent used non-aspirin NSAIDs (which include drugs such as ibuprofen and naproxen/Aleve) and 16 percent used acetaminophen. Those who used aspirin daily had a 20 percent lower risk of ovarian cancer than those who used aspirin less than once a week, the study found. http://healthreviews14.blogspot.com/2014/02/seven-types-of-basic-spices-to-lose.html
The risk of ovarian cancer was 10 percent lower in women who used non-aspirin NSAIDs at least once a week, compared to those who used them less often. However, this difference was not statistically significant, the researchers said.
There was no link between acetaminophen use and ovarian cancer risk, according to the study, which was published Feb. 6 in the Journal of the National Cancer Institute.
The findings add to the growing list of cancers and other diseases aspirin might help protect against, the researchers said. Although the study showed an association between aspirin use and a lower risk of ovarian cancer, it did not prove a cause-and-effect link.
"Our study suggests that aspirin regimens, proven to protect against heart attack, may reduce the risk of ovarian cancer as well," Britton Trabert, of the National Cancer Institute's division of cancer epidemiology, said in a U.S. National Institutes of Health news release.
"However intriguing our results are, they should not influence current clinical practice," Trabert said. "Additional studies are needed to explore the delicate balance of risk and benefit for this potential chemopreventive agent, as well as studies to identify [how] aspirin may reduce ovarian cancer risk."
Regular aspirin use can cause side effects such as bleeding in the digestive tract or hemorrhagic (bleeding) stroke, the study authors said. They also said people should get their doctor's approval before starting to take aspirin daily.
More than 20,000 women in the United States will be diagnosed with ovarian cancer this year, and more than 14,000 will die from the disease.
Researchers from the U.S. National Cancer Institute analyzed data from 12 studies that involved nearly 8,000 women with ovarian cancer and close to 12,000 women without the disease to determine how the use of aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen (Tylenol) affected the risk of ovarian cancer.
About 18 percent of the women used aspirin regularly, 24 percent used non-aspirin NSAIDs (which include drugs such as ibuprofen and naproxen/Aleve) and 16 percent used acetaminophen. Those who used aspirin daily had a 20 percent lower risk of ovarian cancer than those who used aspirin less than once a week, the study found. http://healthreviews14.blogspot.com/2014/02/seven-types-of-basic-spices-to-lose.html
The risk of ovarian cancer was 10 percent lower in women who used non-aspirin NSAIDs at least once a week, compared to those who used them less often. However, this difference was not statistically significant, the researchers said.
There was no link between acetaminophen use and ovarian cancer risk, according to the study, which was published Feb. 6 in the Journal of the National Cancer Institute.
The findings add to the growing list of cancers and other diseases aspirin might help protect against, the researchers said. Although the study showed an association between aspirin use and a lower risk of ovarian cancer, it did not prove a cause-and-effect link.
"Our study suggests that aspirin regimens, proven to protect against heart attack, may reduce the risk of ovarian cancer as well," Britton Trabert, of the National Cancer Institute's division of cancer epidemiology, said in a U.S. National Institutes of Health news release.
"However intriguing our results are, they should not influence current clinical practice," Trabert said. "Additional studies are needed to explore the delicate balance of risk and benefit for this potential chemopreventive agent, as well as studies to identify [how] aspirin may reduce ovarian cancer risk."
Regular aspirin use can cause side effects such as bleeding in the digestive tract or hemorrhagic (bleeding) stroke, the study authors said. They also said people should get their doctor's approval before starting to take aspirin daily.
More than 20,000 women in the United States will be diagnosed with ovarian cancer this year, and more than 14,000 will die from the disease.
Monday, February 3, 2014
Midwives may prescribe medications
Midwives may prescribe medications
The Belgian midwives can now prescribe medication needed to
autonomously perform. Childbirth "This is a huge step forward for the
autonomy and profession of fault of the midwife and offers several advantages
in her profession, says Marlene Reins, president of the Flemish Organization of
Midwives (VLOV).
A midwife guides and monitors organically healthy women and
newborns. A woman can at the midwife visit during pregnancy and during and
after birth. Until now could midwives, either independently or as an employee,
not a prescription medication, but recently published in the Official Gazette
implementing a law requiring medication may prescribe for midwives catch in
childbirth they perform autonomously. urgent situation Certain contraceptive
with breastfeeding midwives can now prescribe. "We now have all the possibilities
to be a good way to do our work and to use the appropriate legal framework
available to us better," said Marlene Lawns (VLOV). http://www.writerscafe.org/writing/jasminejesper370/1307110/
The organization also hopes that implementing making them
appear independently in certain circumstances to perform ultrasounds and pelvic
floor can provide exercises that are currently the physiotherapists for women
after childbirth suffer from their pelvic floor muscles. Midwives can only
prescribe medication if they follow the program "specialized applied
pharmacology" and pass an exam successfully. Midwives who graduate after
October 1, 2014 will already have the necessary competencies.
The 'hangover drip' colds
Cara Delavigne at the 'hangover drip' colds
Model Cara Delavigne and 'BFF' Michelle Rodriguez are now
inseparable. They do everything together and then hung too cozy together at the
'party girl' drip. It is popular with celebrities in the United States because
it would be to soften. Suffered a hangover way The British model would use the
infusion of a concentrated blend of vitamins and minerals in saline to her
cold. Rodriguez and Calamine went this week also put together a day of
paintball.
Riana is also a big fan of the infusion, but then used it
again to heal her. Hangover However, experts are not yet convinced of the
beneficial effects of the hangover infusion. Some believe that it was merely
placebo effects (that depends of course, on the extent to which a needle in
your arm you can do to feel better), and according to others, http://www.mediafire.com/view/1c84obdk3wssoy3/Fibroids%20by%20Amanda%20Leto.docx
it is absolutely
no efficient way to spread in the body. Nutrients "Nutrients insertion
into the blood rather than through the food does not guarantee that they arrive
at the right place," says nutritionist Ian Marker. According to him,
drinking a glass of water as well as effective if you are dehydrated after a
night of drinking
Read also
Popular with stars: tomcat drive with vitamin-infused
Why eyebrow transplants are now so popular
In the pipeline: weekly injection you slowing appetite
Why breakfast (especially for teenagers) is crucial
Why breakfast (especially for teenagers) is crucial
The breakfast appears to be still. Most important meal of
the day It was only recently confirmed by Swedish researchers. The study shows
that mainly breakfast habits during the teenage years, play an important role
in the risk of possible disorders. According to the researchers as adolescent
people who are not or not
sufficiently breakfast three decades later, more
likely to develop from the metabolic syndrome. Have This is a combination of
diabetes, high blood pressure and obesity.
The researchers from the University in Sweden Umea those
visits in 1981, several students at schools in the city of Lulea about their
breakfast habits http://generalhealthblog.fishinblogs.com/2014/01/30/tips-to-burn-100-calories-or-more/
These same
individuals were 27 years later, re-interviewed in 2008, and studied. It was
specifically looked at symptoms of the metabolic syndrome. The metabolic
syndrome increases the risk of heart disease and stroke to diabetes, high bloodpressure or obesity big risks, but a combination of the three is very
dangerous.
Results showed that
persons who as a teenager not eat breakfast or breakfast neglected adult 68%
were more at risk of the metabolic syndrome to suffer.
Although researchers
also looked at other socio-economic factors and the habits of the young people
in question, it was decided that breakfast was the decisive factor. Additional
research is needed mainly abdominal obesity and diabetes were subcomponents
that could be to unhealthy breakfast habits during adolescence directly linked
, said the researchers.
Nutrition experts also found the approach downright dangerous
Nutrition experts also found the approach downright
dangerous. "Comparing yourself to others (your friends, your sister or
colleagues) is a very unhealthy way to judge your own. Weight and a comparison
with celebrities is even worse."
The scales of inquiry would "not
take into account body fat, height, BMI, waist and hip circumference, and
ignore all the rules about what a healthy weight." Massive criticism
Superdrug got the idea not only in the British media, but also on Twitter too
much criticism hear. The chain decided tonight, will not be tested. Scales
following the mostly negative feedback, That the company announced through a
statement on Twitter.
If you share a roller with someone else, you may microbes,
bacteria and fungi on to each other. Stop there, so it, or opt for a spray. 4.
Nail clippers and files If your cuticles are pushed too far back or callus is
removed, you can make small incisions in your skin. These are perfect openings
for bacteria, fungi and viruses, http://generalhealth2014.weebly.com/1/post/2014/01/changing-the-carbohydrate-metabolism-of-the-fat.html
which are exchanged when the instruments are
not cleaned properly. Hepatitis C, staph infections and warts can spread so
easily. 5. Make-up When you know that your girlfriend has an infection such as
a cold sore or conjunctivitis, you will hold your lipstick and mascara better
for yourself. In other cases, it is quite safe to lend them out because most
cosmetics contain preservatives to kill bacteria.
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